AO ProVantage Gel

Real Antioxidants. Real Results. Not Homeopathy.

PerioSciences AO ProVantage Gel contains concentrated antioxidants formulated to support the health of oral soft tissues exposed to oxidative stress — a key contributor to inflammation and delayed healing.

Unlike homeopathic gels that rely on highly diluted botanical ingredients, AO ProVantage delivers two proven antioxidants to complement the body’s natural salivary defense system.

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Why Consider An Antioxidant Alternative?

  • Homeopathic blends can contain dozens of active compounds, creating hundreds of unpredictable interactions.
  • Botanical potency varies widely between harvests—consistency isn’t guaranteed.
  • Some lack clinical trials demonstrating efficacy.

What Professionals Are Saying

I have recommended AO ProVantage Gel to my post-surgical patients for more than 14 years. Patients love the refreshing, soothing effects when they use it as part of their routine home care oral hygiene regimen.

Edward P. Allen, DDS, PhD Periodontist | Dallas, TX

For over 10 years during my lectures and in my prosthodontic practice, I have been recommending the use of topical antioxidants in tandem with esthetic treatment.

Robert Winter, DDS Spear Education and Private Practice

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Tailored Options for Your Practice

We recognize no two practices are the same.
That’s why we offer AO ProVantage Gel in 15 case quantities in two sizes:
Standard (30ml) and On-the-Go (15ml).

The PerioSciences Advantage

AO ProVantage Gel delivers reliable, antioxidant-based soothing benefits––unlike homeopathic blends that may vary in potency and supporting evidence. It is designed for use after routine hygiene visits, periodontal therapy, or oral surgery as a soothing adjunct as tissues recover naturally.

  1. Patented Technology: Incorporates purified antioxidants into its formulas using technology covered by its patent portfolio.
  2. Professional Adoption: Widely used in dental practices and supported by case studies.
  3. Published Evidence: Powered by antioxidant ingredients, Phloretin & Ferulic Acid, studied in multiple peer-reviewed publications1–4.

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Supporting Studies

  1. Fordham J., Naqvi A., et al. “Leukocyte Production of Inflammatory Mediators Is Inhibited by the Antioxidants Phloretin, Silymarin, Hesperetin, and Resveratrol,” Mediators of Inflammation, 2014.
  2. San Miguel S., Svoboda K., et al. “Bioactive Polyphenol Antioxidants Protect Oral Fibroblast From ROS Inducing Agents,” Archives of Oral Biology, 2012.
  3. San Miguel S., Svoboda K., et al. “Bioactive Antioxidant Mixtures Promote Proliferation and Migration on Human Oral Fibroblasts,” Archives of Oral Biology, 2011.
  4. San Miguel S., Svoboda K., et al. “Antioxidants Counteract Nicotine and Promote Migration via RacGTP in Oral Fibroblast Cells,” & Journal of Periodontology, 2010